Yale Researchers Identify Probable Genetic Trigger of Depression

RoseTracker| Researchers believe they have identified a genetic trigger, or at least a key player, in the onset of depression. This health condition affects about 16 percent of Americans annually, disproportionately women, and at an economic cost of $100 billion.

Although antidepressants are widely proscribed in America, about 40 percent of patients don’t respond to current drugs.

Comparing tissue samples between deceased people with known depression and those who didn’t, Ronald S. Duman, professor of psychiatry and pharmacology at Yale and senior author of the study, identified one gene called MKP-1 was increased more than two-fold in the brain tissues of depressed individuals. via Science Daily